Chef Mario Castrellón's flagship. Native Panamanian ingredients, no shortcuts, tasting menus built around things like cacao and mangrove crab. The one non-negotiable reservation for a serious food trip to Panama City.
An intimate El Cangrejo dining room serving a daily-changing, market-driven tasting menu — contemporary Panamanian cooking built around the season's best local produce and seafood.
Live-fire farm-to-table cooking inside the Amarla Casco Viejo Boutique Hotel — every dish shaped by wood flame, seasonal Panamanian ingredients and a kitchen that lets the fire do the talking.
Ranked #5 of 1,224 restaurants in Panama City, 4.9★. Vacuum-aged ropa vieja, grilled octopus in criolla sauce, ribeye finished with Panamanian chimichurri. Live music on weekends.
Chef Carlos \
Panama City's most spectacular rooftop table — perched six floors above Casco Viejo's cobblestones with panoramic skyline views. Fire-kissed steaks, black-ink seafood rice, and flaming cocktails served to a DJ soundtrack. Rated 4.8 on TripAdvisor with 500+ reviews.
Small wine bar in Casco Viejo built around natural wines and whatever's fresh that day. Tight room, short list, food made to go with the glass in front of you.
10–12 course tasting menu at Casa Pérez Alemán in Casco Viejo. Small room, chef cooks in front of you, no menu handed out ahead of time.
14th floor of the JW Marriott in Punta Pacífica. Ceviches and local ingredients done with real technique, terrace overlooks the city — a good pick for a special occasion.
Named on Latin America's 50 Best. Omakase counter, real sake list, the chef controls the pace of the meal.
Ranked #1 of 1,232 restaurants in Panama City on TripAdvisor, 5.0★. Inside the restored Edificio Antiguo Club Unión in Casco Viejo. Panamanian seafood, menu changes with the season.
Panama's only dedicated Afro-Panamanian restaurant — rated 4.9★ with 1,045 reviews, ranked #22 in Panama City, and featured on Latin America's 50 Best. The One Pot Colonense and coconut-braised dishes carry centuries of Afro-Caribbean heritage onto the plate.
Ranked #32 of 1,223 restaurants in Panama City with a 4.9★ rating and TripAdvisor Travelers' Choice. Frank's Place is Panama City's definitive Italian table — handmade pasta, proper bistecca and a wine list that earns the room's quiet sophistication on Calle 53.
5.0★ on TripAdvisor. Basque for 'spices.' Spanish pintxos, fire-roasted seafood, ingredients sourced from Europe and locally.
A refined Panama City table with a focused menu of contemporary small plates — ingredient-led cooking with a precise, modern hand.
A dependable sushi counter on Calle 58 in Obarrio — fresh cuts, clean technique and a loyal following that keeps the dining room full on a Wednesday the same as a Friday.
Wine bar where the food is built to pair with what's being poured, not the other way around. Small, focused list, seasonal menu.
In the shadow of the Metropolitan Cathedral — a Casco Viejo dining room that pairs the old city's colonial grandeur with a thoughtful, contemporary Panamanian menu.
Eleventh-floor sushi sanctuary in Obarrio — nigiri, sashimi and izakaya plates above the city.
Altos del Golf's serious steakhouse — an elegant dark dining room with a sculptural branch chandelier, marble tables and a kitchen built around premium Wagyu. Cuts are sourced carefully and the room earns every bit of its reputation.
Inside a restored colonial monastery in Casco Viejo — brick arches, herringbone ceilings, courtyard seating. Breakfast buffet is one of the best in the city; dinner leans fusion, spicy tuna tartare is what people talk about.